MEDVi starts at $179/mo (all-in, includes medication); DirectMeds at $179/mo (all-in, includes medication). Both prescribe GLP-1 medication — MEDVi offers compounded semaglutide & tirzepatide, DirectMeds compounded semaglutide & tirzepatide. Here's how they compare on price, medications, support and transparency.
Bottom line: MEDVi wins
MEDVi wins on our rubric, 8.2/10 to 8.0/10. It leads most on support. Choose DirectMeds instead if you want the broadest medication menu and the flexibility to switch or adjust dose.
Round by round
We scored both programs on the four factors in our methodology — value, support, medications and transparency. MEDVi takes 2, DirectMeds takes 1, with 1 even. Here's how each shook out.
Value
What you get for the price — not just the lowest sticker. A premium program that includes FDA-approved medication, insurance help and real support can be good value. Evenly matched at about 7.8.
Support
Real clinician access, coaching and follow-up — video visits and a care team score higher than async-only. MEDVi scores 8.0 to 7.2 — clearly ahead.
Medications
Medication options and legitimacy — FDA-approved branded (Wegovy, Zepbound) rates above compounded-only, and breadth and flexibility add points. DirectMeds scores 9.0 to 8.4 — ahead.
Transparency
How clearly and publicly pricing, terms and availability are stated — plus track record and any regulatory red flags. MEDVi scores 8.4 to 8.0 — ahead.
Where they differ most
The clearest daylight is in support, where MEDVi leads 8.0 to 7.2 and medications, where DirectMeds leads 9.0 to 8.4. On price, they start level at $179/mo.
Pricing: MEDVi vs DirectMeds
Both advertise the same starting rate — $179/mo — so price alone won't decide it. Look at the structure: MEDVi is all-in, includes medication, DirectMeds is all-in, includes medication. We unpack how these plans are structured in how much compounded semaglutide costs.
MEDVi: On 12-month prepay; month-to-month is $299/mo; tirzepatide higher (as of 2026, health.usnews.com). DirectMeds: Sublingual/oral semaglutide; injectable semaglutide ~$297/mo, tirzepatide ~$399/mo (as of Sep 2026, clearmetabolic.com).
The specs, side by side
| MEDVi | DirectMeds | |
|---|---|---|
| Editor rating | 8.2/10 · Very good | 8.0/10 · Very good |
| Starting price | $179/mo | $179/mo |
| Pricing | All-in, includes medication | All-in, includes medication |
| Medications | Compounded semaglutide & tirzepatide | Compounded semaglutide & tirzepatide |
| Medication form | Weekly injection | Injection or sublingual |
| Visit type | Async, ~24h provider review | Async, reviewed within ~6h |
| Insurance | Cash-pay (HSA/FSA) | Cash-pay (HSA/FSA) |
| Availability | All 50 states | ~45 states |
Which should you pick?
Choose MEDVi if…
You want stronger clinical support — more clinician time, coaching and follow-up.
View MEDVi plans →Choose DirectMeds if…
You want the broadest medication menu and the flexibility to switch or adjust dose.
View DirectMeds plans →Common questions
Is MEDVi better than DirectMeds?
In our scoring MEDVi comes out ahead — 8.2/10 to 8.0/10, leading on support. It's our pick for most people; DirectMeds is the better choice if you want the broadest medication menu and the flexibility to switch or adjust dose.
Which is cheaper, MEDVi or DirectMeds?
Both advertise the same starting rate — $179/mo — so price alone won't decide it. Look at the structure: MEDVi is all-in, includes medication, DirectMeds is all-in, includes medication.
Do MEDVi and DirectMeds prescribe the same medications?
MEDVi offers compounded semaglutide & tirzepatide (weekly injection); DirectMeds offers compounded semaglutide & tirzepatide (injection or sublingual). On breadth of options, DirectMeds scores higher. Compounded GLP-1s aren't FDA-approved finished products, and availability shifts — confirm current options with each provider.
Which gives you more support, MEDVi or DirectMeds?
MEDVi scores higher on support — real clinician access, coaching and follow-up. For visits, MEDVi is async, ~24h provider review and DirectMeds is async, reviewed within ~6h.
Are MEDVi and DirectMeds legit?
Both require a licensed clinician to review your intake before prescribing. Confirm each provider's credentials, state availability (MEDVi: all 50 states; DirectMeds: ~45 states) and current pricing before you sign up — and note that compounded medications aren't FDA-approved.
Can I switch between MEDVi and DirectMeds?
Generally yes — neither locks you into a long contract, though the lowest prices often require a prepaid plan. Never stop or change a GLP-1 medication without talking to your clinician first.
Both programs are scored with the same independent methodology. We may earn a commission from either provider — it changes nothing about the scores or the verdict. Prices are advertised starting rates as of October 2026; confirm current pricing with each provider. Nothing here is medical advice.